IRDye® 800RS NHS Ester

Basic Information

structure
IRDye® 800RS NHS Ester
918324-94-4
C50 H57 N3 O11 S2 • Na
962.11g / Mol
Cyanine
• Polyprotic molecular weight = 940.13 for mass spectrometry analysis • Near-infrared (NIR) fluorescent dye • Solubility: Water or DMSO • More hydrophobic and less salt-tolerant than IRDye® 800CW • NHS ester for conjugation to amino and hydroxyl groups • Supplied as monosodium salt • Used for making optical probes for NIR fluorescence imaging • Tendency to self-quench via dye-stacking at higher labeling concentrations.

References

1
Synthesis and Biological Evaluation of Low Molecular Weight Fluorescent Imaging Agents for the Prostate-Specific Membrane Antigen, DOI: 10.1021/bc3003919

Overview

767 nm
785 nm
Water PH 6.50
200000 M-1cm-1

Absorption

767 nm
200000 M-1cm-1
-

Emission

785 nm
no
-
-

More parameters

Water PH 6.50
-

spectra uploaded by Lael Cheung

Provide more Spectra

Quantum Yields


Lifetimes


Availabilities

Commercial
LI-COR Biosciences (USA & Worldwide Distributor Information)
http://www.licor.com/bio/products/reagents/irdye/800rs/index.html
biosales@licor.com
Commercial
LI-COR Biosciences GmBH (Germany, Austria, & Switzerland)
http://www.licor.com/bio/products/reagents/irdye/800rs/index.html
bio-eu@licor.com
Commercial
LI-COR Biosciences Ltd (UK, Ireland, Scandinavia, & Iceland)
http://www.licor.com/bio/products/reagents/irdye/800rs/index.html
bio-eu@licor.com
Commercial
Japan: M&S TechnoSystems, Inc.
http://www.mstechno.co.jp/
technosales@technosaurus.co.jp
Commercial
China: Gene Company Ltd.
http://www.genecompany.com/
sales@genehk.com
Commercial
South Korea: Dong Young Instruments Co., Ltd.
http://www.dongyoung.co.kr/sub/index.php
product@dongyoung.co.kr
Commercial
Australia: Millennium Science Pty. Ltd.
http://www.mscience.com.au/
sales@mscience.com.au
Commercial
India: Inkarp Instruments Pvt. Ltd.
http://inkarp.co.in/
info@inkarp.co.in

Applications

fluorescent labeling
Structural Features of a Picornavirus Polymerase Involved in the Polyadenylation of Viral RNA
10.1128/JVI.02590-12
Photoacoustic imaging
Synthesis and Testing of Modular Dual-Modality Nanoparticles for Magnetic Resonance and Multispectral Photoacoustic Imaging
10.1021/acs.bioconjchem.5b00633
RNA labeling
Structure-Function Relationships Underlying the Replication Fidelity of Viral RNA-Dependent RNA Polymerases
10.1128/JVI.01574-14
fluorescent labeling
In Vivo Gene-Silencing in Fibrotic Liver by siRNA-Loaded Cationic Nanohydrogel Particles
10.1002/adhm.201500826